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Mining Public Toxicogenomic Data Reveals Insights and Challenges in Delineating Liver Steatosis Adverse Outcome Pathways
Exposure to chemicals contributes to the development and progression of fatty liver, or steatosis, a process characterized by abnormal accumulation of lipids within liver cells. However, lack of knowledge on how chemicals cause steatosis has prevented any large-scale assessment of the 80,000+ chemic...
Autores principales: | AbdulHameed, Mohamed Diwan M., Pannala, Venkat R., Wallqvist, Anders |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813744/ https://www.ncbi.nlm.nih.gov/pubmed/31681434 http://dx.doi.org/10.3389/fgene.2019.01007 |
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