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The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis
Two types of monocytes, Ly6C(hi) and Ly6C(lo), infiltrate the heart in murine experimental autoimmune myocarditis (EAM). We discovered a role for cardiac fibroblasts in facilitating monocyte-to-macrophage differentiation of both Ly6C(hi) and Ly6C(lo) cells, allowing these macrophages to perform dive...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813836/ https://www.ncbi.nlm.nih.gov/pubmed/31269438 http://dx.doi.org/10.1016/j.celrep.2019.06.007 |