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The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis

Two types of monocytes, Ly6C(hi) and Ly6C(lo), infiltrate the heart in murine experimental autoimmune myocarditis (EAM). We discovered a role for cardiac fibroblasts in facilitating monocyte-to-macrophage differentiation of both Ly6C(hi) and Ly6C(lo) cells, allowing these macrophages to perform dive...

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Detalles Bibliográficos
Autores principales: Hou, Xuezhou, Chen, Guobao, Bracamonte-Baran, William, Choi, Hee Sun, Diny, Nicola L., Sung, Jungeun, Hughes, David, Won, Taejoon, Wood, Megan Kay, Talor, Monica V., Hackam, David Joel, Klingel, Karin, Davogustto, Giovanni, Taegtmeyer, Heinrich, Coppens, Isabelle, Barin, Jobert G., Čiháková, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813836/
https://www.ncbi.nlm.nih.gov/pubmed/31269438
http://dx.doi.org/10.1016/j.celrep.2019.06.007