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iPSC-derived homogeneous populations of developing schizophrenia cortical interneurons have compromised mitochondrial function

Schizophrenia (SCZ) is a neurodevelopmental disorder. Thus, studying pathogenetic mechanisms underlying SCZ requires studying the development of brain cells. Cortical interneurons (cINs) are consistently observed to be abnormal in SCZ postmortem brains. These abnormalities may explain altered gamma...

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Detalles Bibliográficos
Autores principales: Ni, Peiyan, Noh, Haneul, Park, Gun-Hoo, Shao, Zhicheng, Guan, Youxin, Park, James M., Yu, Sophy, Park, Joy S., Coyle, Joseph T., Weinberger, Daniel R., Straub, Richard E., Cohen, Bruce M., McPhie, Donna L., Yin, Changhong, Huang, Weihua, Kim, Hae-Young, Chung, Sangmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813882/
https://www.ncbi.nlm.nih.gov/pubmed/31019265
http://dx.doi.org/10.1038/s41380-019-0423-3