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The Tripeptide RER Mimics Secreted Amyloid Precursor Protein-Alpha in Upregulating LTP
Secreted amyloid precursor protein-alpha (sAPPα), generated by enzymatic processing of the APP, possesses a range of neurotrophic and neuroprotective properties and plays a critical role in the molecular mechanisms of memory and learning. One of the key active regions of sAPPα is the central APP dom...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813913/ https://www.ncbi.nlm.nih.gov/pubmed/31680870 http://dx.doi.org/10.3389/fncel.2019.00459 |