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The Tripeptide RER Mimics Secreted Amyloid Precursor Protein-Alpha in Upregulating LTP

Secreted amyloid precursor protein-alpha (sAPPα), generated by enzymatic processing of the APP, possesses a range of neurotrophic and neuroprotective properties and plays a critical role in the molecular mechanisms of memory and learning. One of the key active regions of sAPPα is the central APP dom...

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Detalles Bibliográficos
Autores principales: Morrissey, Jodi A., Bigus, Erin, Necarsulmer, Julie C., Srinivasan, Vinay, Peppercorn, Katie, O’Leary, Daniel J., Mockett, Bruce G., Tate, Warren P., Hughes, Stephanie M., Parfitt, Karen D., Abraham, Wickliffe C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813913/
https://www.ncbi.nlm.nih.gov/pubmed/31680870
http://dx.doi.org/10.3389/fncel.2019.00459