Cargando…

The Tripeptide RER Mimics Secreted Amyloid Precursor Protein-Alpha in Upregulating LTP

Secreted amyloid precursor protein-alpha (sAPPα), generated by enzymatic processing of the APP, possesses a range of neurotrophic and neuroprotective properties and plays a critical role in the molecular mechanisms of memory and learning. One of the key active regions of sAPPα is the central APP dom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morrissey, Jodi A., Bigus, Erin, Necarsulmer, Julie C., Srinivasan, Vinay, Peppercorn, Katie, O’Leary, Daniel J., Mockett, Bruce G., Tate, Warren P., Hughes, Stephanie M., Parfitt, Karen D., Abraham, Wickliffe C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813913/ https://www.ncbi.nlm.nih.gov/pubmed/31680870 http://dx.doi.org/10.3389/fncel.2019.00459

Ejemplares similares

Secreted Amyloid Precursor Protein-Alpha Enhances LTP Through the Synthesis and Trafficking of Ca(2+)-Permeable AMPA Receptors
por: Livingstone, Rhys W., et al.
Publicado: (2021)

Lentivirus-mediated expression of human secreted amyloid precursor protein-alpha prevents development of memory and plasticity deficits in a mouse model of Alzheimer's disease
por: Tan, Valerie T. Y., et al.
Publicado: (2018)

Therapeutic Potential of Secreted Amyloid Precursor Protein APPsα
por: Mockett, Bruce G., et al.
Publicado: (2017)

Secreted Amyloid Precursor Protein-Alpha Promotes Arc Protein Synthesis in Hippocampal Neurons
por: Livingstone, Rhys W., et al.
Publicado: (2019)

Time-dependent changes in gene expression induced by secreted amyloid precursor protein-alpha in the rat hippocampus
por: Ryan, Margaret M, et al.
Publicado: (2013)

Secreted Amyloid Precursor Protein Alpha (sAPPα Regulates the Cellular Proteome and Secretome of Mouse Primary Astrocytes
por: Peppercorn, Katie, et al.
Publicado: (2023)

The amyloid-beta forming tripeptide cleavage mechanism of γ-secretase
por: Bolduc, David M, et al.
Publicado: (2016)

Dieter Sturhan Dr. Rer. Nat. (1936 – 2017)
por: Lišková, Marta, et al.
Publicado: (2018)

The Microwave Rotational Electric Resonance (RER) Spectrum of Benzothiazole
por: Hadki, Hamza El, et al.
Publicado: (2023)

Effect of soluble amyloid precursor protein-alpha on adult hippocampal neurogenesis in a mouse model of Alzheimer’s disease
por: Ohline, Shane M., et al.
Publicado: (2022)

Secreted Amyloid Precursor Protein Alpha, a Neuroprotective Protein in the Brain Has Widespread Effects on the Transcriptome and Proteome of Human Inducible Pluripotent Stem Cell-Derived Glutamatergic Neurons Related to Memory Mechanisms
por: Peppercorn, Katie, et al.
Publicado: (2022)

Chemogenetic regulation of the TARP-lipid interaction mimics LTP and reversibly modifies behavior
por: Park, Joongkyu, et al.
Publicado: (2023)

RER1 enhances carcinogenesis and stemness of pancreatic cancer under hypoxic environment
por: Chen, Shi, et al.
Publicado: (2019)

Endoplasmic reticulum localization of Sec12p is achieved by two mechanisms: Rer1p-dependent retrieval that requires the transmembrane domain and Rer1p-independent retention that involves the cytoplasmic domain
Publicado: (1996)

QSAR Study on Antioxidant Tripeptides and the Antioxidant Activity of the Designed Tripeptides in Free Radical Systems
por: Chen, Nan, et al.
Publicado: (2018)

A Voltage-Based STDP Rule Combined with Fast BCM-Like Metaplasticity Accounts for LTP and Concurrent “Heterosynaptic” LTD in the Dentate Gyrus In Vivo
por: Jedlicka, Peter, et al.
Publicado: (2015)

The ER retention protein RER1 promotes alpha-synuclein degradation via the proteasome
por: Park, Hyo-Jin, et al.
Publicado: (2017)

Tripeptide analysis of protein structures
por: Anishetty, Sharmila, et al.
Publicado: (2002)

Acute intracerebral treatment with amyloid-beta (1–42) alters the profile of neuronal oscillations that accompany LTP induction and results in impaired LTP in freely behaving rats
por: Kalweit, Alexander Nikolai, et al.
Publicado: (2015)

Amyloid-β oligomers suppress subunit-specific glutamate receptor increase during LTP
por: Tanaka, Hiromitsu, et al.
Publicado: (2019)

Rer1p regulates the ER retention of immature rhodopsin and modulates its intracellular trafficking
por: Yamasaki, Akinori, et al.
Publicado: (2014)

Combined LTP Sublingual and Oral Immunotherapy in LTP Syndrome: Efficacy and Safety
por: Martin Iglesias, Maria Aranzazu, et al.
Publicado: (2023)

Redistribution of Ionotropic Glutamate Receptors Detected by Laser Microdissection of the Rat Dentate Gyrus 48 h following LTP Induction In Vivo
por: Kennard, Jeremy T. T., et al.
Publicado: (2014)

Partial Endothelial Nitric Oxide Synthase Deficiency Exacerbates Cognitive Deficit and Amyloid Pathology in the APPswe/PS1ΔE9 Mouse Model of Alzheimer’s Disease
por: Ahmed, Sara, et al.
Publicado: (2022)

Amyloid precursor protein and amyloid precursor-like protein 2 in cancer
por: Pandey, Poomy, et al.
Publicado: (2016)

Controversy of Peptide Cyclization from Tripeptide
por: Lin, Chung-Yin, et al.
Publicado: (2021)

The amyloid precursor protein: beyond amyloid
por: Zheng, Hui, et al.
Publicado: (2006)

Amyloid β-Sheet Mimics that Antagonize Amyloid Aggregation and Reduce Amyloid Toxicity
por: Cheng, Pin-Nan, et al.
Publicado: (2012)

The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels
por: Valkova, Christina, et al.
Publicado: (2017)

Isolation and Functional Analysis of ZmLTP3, a Homologue to Arabidopsis LTP3
por: Zou, Hua-Wen, et al.
Publicado: (2013)

The tripeptide feG inhibits leukocyte adhesion
por: Mathison, Ronald D, et al.
Publicado: (2008)

A conserved tripeptide sorts proteins to peroxisomes
Publicado: (1989)

Modulation of neutrophil function by the tripeptide feG
por: Mathison, Ronald D, et al.
Publicado: (2003)

Synthesis of trifunctional cyclo-β-tripeptide templates
por: Stein, Frank, et al.
Publicado: (2012)

Effect of Collagen Tripeptide on Atherosclerosis in Healthy Humans
por: Tomosugi, Naohisa, et al.
Publicado: (2017)

Supramolecular Tripeptide Hydrogel Assembly with 5-Fluorouracil
por: Parisi, Evelina, et al.
Publicado: (2019)

Furan-Conjugated Tripeptides as Potent Antitumor Drugs
por: Ali, Hunain, et al.
Publicado: (2020)

Copper–tripeptides (cuzymes) with peroxidase-mimetic activity
por: Nguyen, Le Truc, et al.
Publicado: (2020)

Prevalence of HBsAg and high-risk behaviors in pregnant women rerring to Urban Health Centers in Isfahan province
por: Ahmadi, Mahboubeh, et al.
Publicado: (2011)

Protein quality control by Rer1p in the early secretory pathway: from mechanism to implication in Alzheimer’s disease
por: Jurisch-Yaksi, Nathalie, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_jemv8oetcatmpo66mu3vvmmk24