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Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesis
BACKGROUND: Systemic sclerosis (SSc) is a rare autoimmune connective tissue disease whose pathogenesis remains incompletely understood. Increasing evidence suggests that both genetic susceptibilities and changes in DNA methylation influence pivotal biological pathways and thereby contribute to the d...
Autores principales: | Lu, Tianyuan, Klein, Kathleen Oros, Colmegna, Inés, Lora, Maximilien, Greenwood, Celia M. T., Hudson, Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813992/ https://www.ncbi.nlm.nih.gov/pubmed/31651337 http://dx.doi.org/10.1186/s12920-019-0602-8 |
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