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Micelles Loaded With Puerarin And Modified With Triphenylphosphonium Cation Possess Mitochondrial Targeting And Demonstrate Enhanced Protective Effect Against Isoprenaline-Induced H9c2 Cells Apoptosis

BACKGROUND: The protective role of puerarin (PUE) against myocardial infarction is closely related to its regulation on mitochondria. However, free PUE can hardly reach the mitochondria of ischemic cardiomyocytes due to the lack of mitochondrial targeting of PUE. Here PUE was loaded into mitochondri...

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Detalles Bibliográficos
Autores principales: Li, Wen-qun, Wu, Jun-yong, Xiang, Da-xiong, Luo, Shi-lin, Hu, Xiong-bin, Tang, Tian-tian, Sun, Tao-li, Liu, Xin-yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814317/
https://www.ncbi.nlm.nih.gov/pubmed/31695371
http://dx.doi.org/10.2147/IJN.S219670