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Micelles Loaded With Puerarin And Modified With Triphenylphosphonium Cation Possess Mitochondrial Targeting And Demonstrate Enhanced Protective Effect Against Isoprenaline-Induced H9c2 Cells Apoptosis
BACKGROUND: The protective role of puerarin (PUE) against myocardial infarction is closely related to its regulation on mitochondria. However, free PUE can hardly reach the mitochondria of ischemic cardiomyocytes due to the lack of mitochondrial targeting of PUE. Here PUE was loaded into mitochondri...
Autores principales: | Li, Wen-qun, Wu, Jun-yong, Xiang, Da-xiong, Luo, Shi-lin, Hu, Xiong-bin, Tang, Tian-tian, Sun, Tao-li, Liu, Xin-yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814317/ https://www.ncbi.nlm.nih.gov/pubmed/31695371 http://dx.doi.org/10.2147/IJN.S219670 |
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