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The secreted kinase ROP17 promotes Toxoplasma gondii dissemination by hijacking monocyte tissue migration

The protozoan parasite Toxoplasma gondii is thought to exploit monocyte trafficking to facilitate dissemination across endothelial barriers such as the blood-brain barrier. Here we analyzed the migration of parasitized monocytes in model endothelial and interstitial environments. We report that infe...

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Detalles Bibliográficos
Autores principales: Drewry, Lisa L, Jones, Nathaniel G, Wang, Quiling, Onken, Michael D, Miller, Mark J, Sibley, L David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814536/
https://www.ncbi.nlm.nih.gov/pubmed/31332383
http://dx.doi.org/10.1038/s41564-019-0504-8