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A molecular sub-cluster of colon cancer cells with low VDR expression is sensitive to chemotherapy, BRAF inhibitors and PI3K-mTOR inhibitors treatment

Gene expression based consensus molecular subtypes (CMS) and non-negative matrix factorization (NMF) sub-clusters are robust colon cancer classification systems. Although, the molecular features are clear, colon cancer subgroups based interventions are limited. To address this problem, we analyze th...

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Detalles Bibliográficos
Autores principales: Wang, Haiwei, Wang, Xinrui, Xu, Liangpu, Zhang, Ji, Cao, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814605/
https://www.ncbi.nlm.nih.gov/pubmed/31596728
http://dx.doi.org/10.18632/aging.102349