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Probucol, a “non-statin” cholesterol-lowering drug, ameliorates D-galactose induced cognitive deficits by alleviating oxidative stress via Keap1/Nrf2 signaling pathway in mice

Oxidative stress plays a vital role in the initiation and progression of age-related neurodegenerative diseases. Ameliorating oxidative damage is therefore considered as a beneficial strategy for the treatment of age-related neurodegenerative disorders. Probucol (Prob), a lipid-lowering prototype ag...

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Detalles Bibliográficos
Autores principales: Huang, Jin-Lan, Yu, Chao, Su, Min, Yang, Si-Man, Zhang, Fan, Chen, Yuan-Yuan, Liu, Jin-Yuan, Jiang, Yi-Fan, Zhong, Zhen-Guo, Wu, Deng-Pan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814622/
https://www.ncbi.nlm.nih.gov/pubmed/31590160
http://dx.doi.org/10.18632/aging.102337