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Development of In Vitro–In Vivo Correlation for Upadacitinib Extended-Release Tablet Formulation
Upadacitinib is a selective Janus Kinase 1 inhibitor which is being developed for the treatment of several inflammatory diseases including rheumatoid arthritis. Upadacitinib was evaluated in Phase 3 studies as an oral extended-release (ER) formulation administered once daily. The purpose of this stu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814631/ https://www.ncbi.nlm.nih.gov/pubmed/31654328 http://dx.doi.org/10.1208/s12248-019-0378-y |