Cargando…

Binding partner- and force-promoted changes in αE-catenin conformation probed by native cysteine labeling

Adherens Junctions (AJs) are cell-cell adhesion complexes that sense and propagate mechanical forces by coupling cadherins to the actin cytoskeleton via β-catenin and the F-actin binding protein αE-catenin. When subjected to mechanical force, the cadherin•catenin complex can tightly link to F-actin...

Descripción completa

Detalles Bibliográficos
Autores principales: Terekhova, Ksenia, Pokutta, Sabine, Kee, Yee S., Li, Jing, Tajkhorshid, Emad, Fuller, Gerald, Dunn, Alexander R., Weis, William I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814714/
https://www.ncbi.nlm.nih.gov/pubmed/31653927
http://dx.doi.org/10.1038/s41598-019-51816-3