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Binding partner- and force-promoted changes in αE-catenin conformation probed by native cysteine labeling
Adherens Junctions (AJs) are cell-cell adhesion complexes that sense and propagate mechanical forces by coupling cadherins to the actin cytoskeleton via β-catenin and the F-actin binding protein αE-catenin. When subjected to mechanical force, the cadherin•catenin complex can tightly link to F-actin...
Autores principales: | Terekhova, Ksenia, Pokutta, Sabine, Kee, Yee S., Li, Jing, Tajkhorshid, Emad, Fuller, Gerald, Dunn, Alexander R., Weis, William I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814714/ https://www.ncbi.nlm.nih.gov/pubmed/31653927 http://dx.doi.org/10.1038/s41598-019-51816-3 |
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