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Biological process activity transformation of single cell gene expression for cross-species alignment

The maintenance and transition of cellular states are controlled by biological processes. Here we present a gene set-based transformation of single cell RNA-Seq data into biological process activities that provides a robust description of cellular states. Moreover, as these activities represent spec...

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Detalles Bibliográficos
Autores principales: Ding, Hongxu, Blair, Andrew, Yang, Ying, Stuart, Joshua M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814736/
https://www.ncbi.nlm.nih.gov/pubmed/31653878
http://dx.doi.org/10.1038/s41467-019-12924-w