Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour

Innate immune chemoreceptors of the formyl peptide receptor (Fpr) family are expressed by vomeronasal sensory neurons (VSNs) in the accessory olfactory system. Their biological function and coding mechanisms remain unknown. We show that mouse Fpr3 (Fpr-rs1) recognizes the core peptide motif f-MKKFRW...

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Detalles Bibliográficos
Autores principales: Bufe, Bernd, Teuchert, Yannick, Schmid, Andreas, Pyrski, Martina, Pérez-Gómez, Anabel, Eisenbeis, Janina, Timm, Thomas, Ishii, Tomohiro, Lochnit, Günter, Bischoff, Markus, Mombaerts, Peter, Leinders-Zufall, Trese, Zufall, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814738/
https://www.ncbi.nlm.nih.gov/pubmed/31653840
http://dx.doi.org/10.1038/s41467-019-12842-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814738/
https://www.ncbi.nlm.nih.gov/pubmed/31653840
http://dx.doi.org/10.1038/s41467-019-12842-x

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