Phase separation-deficient TDP43 remains functional in splicing

Intrinsically disordered regions (IDRs) are often fast-evolving protein domains of low sequence complexity that can drive phase transitions and are commonly found in many proteins associated with neurodegenerative diseases, including the RNA processing factor TDP43. Yet, how phase separation contrib...

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Detalles Bibliográficos
Autores principales: Schmidt, Hermann Broder, Barreau, Ariana, Rohatgi, Rajat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814767/
https://www.ncbi.nlm.nih.gov/pubmed/31653829
http://dx.doi.org/10.1038/s41467-019-12740-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814767/
https://www.ncbi.nlm.nih.gov/pubmed/31653829
http://dx.doi.org/10.1038/s41467-019-12740-2

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