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MT1-MMP directs force-producing proteolytic contacts that drive tumor cell invasion

Unraveling the mechanisms that govern the formation and function of invadopodia is essential towards the prevention of cancer spread. Here, we characterize the ultrastructural organization, dynamics and mechanical properties of collagenotytic invadopodia forming at the interface between breast cance...

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Detalles Bibliográficos
Autores principales: Ferrari, Robin, Martin, Gaëlle, Tagit, Oya, Guichard, Alan, Cambi, Alessandra, Voituriez, Raphaël, Vassilopoulos, Stéphane, Chavrier, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814785/
https://www.ncbi.nlm.nih.gov/pubmed/31653854
http://dx.doi.org/10.1038/s41467-019-12930-y