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Integrin α11 cytoplasmic tail is required for FAK activation to initiate 3D cell invasion and ERK-mediated cell proliferation

Integrin α11β1 is a collagen-binding integrin, which is receiving increasing attention in the context of wound healing and fibrosis. Although α11β1 integrin displays similar collagen specificity to α2β1 integrin, both integrins have distinct in vivo functions. In this context, the contribution of α1...

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Detalles Bibliográficos
Autores principales: Erusappan, Pugazendhi, Alam, Jahedul, Lu, Ning, Zeltz, Cédric, Gullberg, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814791/
https://www.ncbi.nlm.nih.gov/pubmed/31653900
http://dx.doi.org/10.1038/s41598-019-51689-6