C-terminal–modified LY2510924: a versatile scaffold for targeting C-X-C chemokine receptor type 4

C-X-C chemokine receptor type 4 (CXCR4) constitutes a promising target for tumor diagnosis and therapy. Herein, we evaluate a new 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA)-conjugated CXCR4 antagonist derived from LY2510924, FRM001, and its metal complexes as CXCR4-targeting pro...

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Detalles Bibliográficos
Autores principales: Suzuki, Kentaro, Ui, Takashi, Nagano, Akio, Hino, Akihiro, Arano, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814797/
https://www.ncbi.nlm.nih.gov/pubmed/31653903
http://dx.doi.org/10.1038/s41598-019-51754-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814797/
https://www.ncbi.nlm.nih.gov/pubmed/31653903
http://dx.doi.org/10.1038/s41598-019-51754-0

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