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Invariant NKT cells facilitate cytotoxic T-cell activation via direct recognition of CD1d on T cells

Invariant natural killer T (iNKT) cells are a major subset of NKT cells that recognize foreign and endogenous lipid antigens presented by CD1d. Although iNKT cells are characteristically autoreactive to self-antigens, the role of iNKT cells in the regulation of cytotoxic T lymphocytes (CTL) has been...

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Detalles Bibliográficos
Autores principales: Qin, Yingyu, Oh, Sejin, Lim, Sojung, Shin, Jung Hoon, Yoon, Min Sang, Park, Se-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814837/
https://www.ncbi.nlm.nih.gov/pubmed/31653827
http://dx.doi.org/10.1038/s12276-019-0329-9