Distinct downstream signaling and the roles of VEGF and PlGF in high glucose-mediated injuries of human retinal endothelial cells in culture

Vascular endothelial growth factor (VEGF) and placental growth factor (PlGF) plays a crucial role in breakdown of the blood-retinal barrier due to hyperpermeability in diabetic retinopathy (DR). However, the distinct signaling driven by VEGF and PlGF in the pathogenesis of DR remains unclear. In thi...

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Detalles Bibliográficos
Autores principales: Jiao, Wanzhen, Ji, Jia-Fu, Xu, Wenwen, Bu, Wenjuan, Zheng, Yuanjie, Ma, Aihua, Zhao, Bojun, Fan, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814860/
https://www.ncbi.nlm.nih.gov/pubmed/31653890
http://dx.doi.org/10.1038/s41598-019-51603-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814860/
https://www.ncbi.nlm.nih.gov/pubmed/31653890
http://dx.doi.org/10.1038/s41598-019-51603-0

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