Cargando…

Distinct downstream signaling and the roles of VEGF and PlGF in high glucose-mediated injuries of human retinal endothelial cells in culture

Vascular endothelial growth factor (VEGF) and placental growth factor (PlGF) plays a crucial role in breakdown of the blood-retinal barrier due to hyperpermeability in diabetic retinopathy (DR). However, the distinct signaling driven by VEGF and PlGF in the pathogenesis of DR remains unclear. In thi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiao, Wanzhen, Ji, Jia-Fu, Xu, Wenwen, Bu, Wenjuan, Zheng, Yuanjie, Ma, Aihua, Zhao, Bojun, Fan, Qingfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814860/ https://www.ncbi.nlm.nih.gov/pubmed/31653890 http://dx.doi.org/10.1038/s41598-019-51603-0

Ejemplares similares

PlGF, immune system and hypertension
por: Carnevale, Daniela, et al.
Publicado: (2015)

Concentrations of VEGF and PlGF Decrease in Eyes After Intravitreal Conbercept Injection
por: Zhou, Jun, et al.
Publicado: (2018)

Physical activity differentially regulates VEGF, PlGF, and their receptors in the human placenta
por: Bhattacharjee, Jayonta, et al.
Publicado: (2021)

PlGF Immunological Impact during Pregnancy
por: Albonici, Loredana, et al.
Publicado: (2020)

A comparison of the diagnostic utility of the sFlt-1/PlGF ratio versus PlGF alone for the detection of preeclampsia/HELLP syndrome
por: Stepan, H., et al.
Publicado: (2016)

sFLT1, PlGF, the sFLT1/PlGF Ratio and Their Association with Pre-Eclampsia in Twin Pregnancies—A Review of the Literature
por: Sapantzoglou, Ioakeim, et al.
Publicado: (2023)

Changes in concentrations of melatonin, PlGF, and cytokines in women with preeclampsia
por: Savka, Ruslan Florovych, et al.
Publicado: (2023)

Accurate Prediction of Total PlGF (Placental Growth Factor) From Free PlGF and sFlt-1 (Soluble Fms-Like Tyrosine Kinase-1): Evidence for Markedly Elevated PlGF Levels in Women With Acute Fatty Liver of Pregnancy
por: Neuman, Rugina I., et al.
Publicado: (2021)

Activator protein-1 contributes to the NaCl-induced expression of VEGF and PlGF in RPE cells
por: Kleiner, Jana, et al.
Publicado: (2018)

Inhibition of Stromal PlGF Suppresses the Growth of Prostate Cancer Xenografts
por: Zins, Karin, et al.
Publicado: (2013)

Efficiency of sFlt-1/PlGF Ratio in Preeclampsia Diagnosis
por: Tataru-Copos, Anca-Florina, et al.
Publicado: (2022)

Reduced expression in preterm birth of sFLT-1 and PlGF with a high sFLT-1/PlGF ratio in extracellular vesicles suggests a potential biomarker
por: Hussein, Sama, et al.
Publicado: (2022)

Soluble Flt-1 and PlGF: New Markers of Early Pregnancy Loss?
por: Muttukrishna, Shanthi, et al.
Publicado: (2011)

PlGF Reduction Compromises Angiogenesis in Diabetic Foot Disease Through Macrophages
por: Zhu, Lingyan, et al.
Publicado: (2021)

Correlation of sFlt/PlGF ratio with severity of preeclampsia in an Indian population
por: Kumar, Namrata, et al.
Publicado: (2023)

PlGF mediates neutrophil elastase-induced airway epithelial cell apoptosis and emphysema
por: Hou, Hsin-Han, et al.
Publicado: (2014)

Expression of Livin and PlGF in human osteosarcoma is associated with tumor progression and clinical outcome
por: Sun, Kuo, et al.
Publicado: (2018)

Serum PlGF and EGF are independent prognostic markers in non-metastatic colorectal cancer
por: Schölch, Sebastian, et al.
Publicado: (2019)

Diagnostic accuracy of sFlt1/PlGF ratio as a marker for preeclampsia
por: Nikuei, Pooneh, et al.
Publicado: (2020)

Placental and maternal sFlt1/PlGF expression in gestational diabetes mellitus
por: Nuzzo, Anna Maria, et al.
Publicado: (2021)

The sFlt-1/PlGF Ratio in Pregnant Patients Affected by COVID-19
por: Kosinska-Kaczynska, Katarzyna, et al.
Publicado: (2023)

Evaluation of Angiogenic Factors (PlGF and sFlt-1) in Pre-eclampsia Diagnosis
por: Sá, Catherine Primo Nogueira de, et al.
Publicado: (2020)

PlGF and VEGF-A Regulate Growth of High-Risk MYCN-Single Copy Neuroblastoma Xenografts via Different Mechanisms
por: Zins, Karin, et al.
Publicado: (2016)

PB101, a VEGF- and PlGF-targeting decoy protein, enhances antitumor immunity and suppresses tumor progression and metastasis
por: Go, Eun-Jin, et al.
Publicado: (2023)

Dysregulated Serum Lipid Metabolism Promotes the Occurrence and Development of Diabetic Retinopathy Associated With Upregulated Circulating Levels of VEGF-A, VEGF-D, and PlGF
por: Zhang, Xinyuan, et al.
Publicado: (2021)

Difference of concentration of placental soluble fms-like tyrosine kinase-1(sFlt-1), placental growth factor (PlGF), and sFlt-1/PlGF ratio in severe preeclampsia and normal pregnancy
por: Gurnadi, Jeffry Iman, et al.
Publicado: (2015)

Increased sFlt-1 to PlGF Ratio in Women Who Subsequently Develop Preeclampsia
por: Kim, Shin-Young, et al.
Publicado: (2007)

sFlt‐1/PlGF ratio test for pre‐eclampsia: an economic assessment for the UK
por: Vatish, M., et al.
Publicado: (2016)

Gestational diabetes modifies the association between PlGF in early pregnancy and preeclampsia in women with obesity
por: Vieira, Matias C., et al.
Publicado: (2018)

Proteomics reveals ablation of PlGF increases antioxidant and neuroprotective proteins in the diabetic mouse retina
por: Saddala, Madhu Sudhana, et al.
Publicado: (2018)

Multifaceted Role of the Placental Growth Factor (PlGF) in the Antitumor Immune Response and Cancer Progression
por: Albonici, Loredana, et al.
Publicado: (2019)

PD-L1-directed PlGF/VEGF blockade synergizes with chemotherapy by targeting CD141(+) cancer-associated fibroblasts in pancreatic cancer
por: Kim, Duk Ki, et al.
Publicado: (2022)

Economic assessment of the use of the sFlt-1/PlGF ratio test to predict preeclampsia in Germany
por: Schlembach, Dietmar, et al.
Publicado: (2018)

Influence of the sFlt-1/PlGF Ratio on Clinical Decision-Making in Women with Suspected Preeclampsia
por: Klein, Evelyn, et al.
Publicado: (2016)

sFlt-1/PlGF ratio in hypertensive disorders of pregnancy in patients affected by COVID-19
por: Soldavini, Chiara Maria, et al.
Publicado: (2022)

sFlt-1, Not PlGF, Is Related to Twin Gestation Choronicity in the First and Third Trimesters of Pregnancy
por: Kozłowski, Szymon, et al.
Publicado: (2021)

The Impact of Increased Maternal sFlt-1/PlGF Ratio on Motor Outcome of Preterm Infants
por: Middendorf, Lisa, et al.
Publicado: (2022)

The Association of IL-17 and PlGF/sENG Ratio in Pre-Eclampsia and Adverse Pregnancy Outcomes
por: Darmochwal-Kolarz, Dorota, et al.
Publicado: (2022)

Predictive value of the sFlt-1/PlGF ratio in women with suspected preeclampsia: An update (Review)
por: Velegrakis, Alexandros, et al.
Publicado: (2023)

(18)F-FET MicroPET and MicroMRI for Anti-VEGF and Anti-PlGF Response Assessment in an Orthotopic Murine Model of Human Glioblastoma
por: Nedergaard, Mette Kjoelhede, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ik3u5meosahialv1phc9317f7h