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Use of the kojA promoter, involved in kojic acid biosynthesis, for polyketide production in Aspergillus oryzae: implications for long-term production

BACKGROUND: Aspergillus oryzae, a useful industrial filamentous fungus, produces limited varieties of secondary metabolites, such as kojic acid. Thus, for the production of valuable secondary metabolites by genetic engineering, the species is considered a clean host, enabling easy purification from...

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Detalles Bibliográficos
Autores principales: Tamano, Koichi, Kuninaga, Mahoko, Kojima, Naoshi, Umemura, Myco, Machida, Masayuki, Koike, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814975/
https://www.ncbi.nlm.nih.gov/pubmed/31655589
http://dx.doi.org/10.1186/s12896-019-0567-x