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Use of the kojA promoter, involved in kojic acid biosynthesis, for polyketide production in Aspergillus oryzae: implications for long-term production
BACKGROUND: Aspergillus oryzae, a useful industrial filamentous fungus, produces limited varieties of secondary metabolites, such as kojic acid. Thus, for the production of valuable secondary metabolites by genetic engineering, the species is considered a clean host, enabling easy purification from...
Autores principales: | Tamano, Koichi, Kuninaga, Mahoko, Kojima, Naoshi, Umemura, Myco, Machida, Masayuki, Koike, Hideaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814975/ https://www.ncbi.nlm.nih.gov/pubmed/31655589 http://dx.doi.org/10.1186/s12896-019-0567-x |
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