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7C: Computational Chromosome Conformation Capture by Correlation of ChIP-seq at CTCF motifs
BACKGROUND: Knowledge of the three-dimensional structure of the genome is necessary to understand how gene expression is regulated. Recent experimental techniques such as Hi-C or ChIA-PET measure long-range chromatin interactions genome-wide but are experimentally elaborate, have limited resolution...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814980/ https://www.ncbi.nlm.nih.gov/pubmed/31653198 http://dx.doi.org/10.1186/s12864-019-6088-0 |