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7C: Computational Chromosome Conformation Capture by Correlation of ChIP-seq at CTCF motifs

BACKGROUND: Knowledge of the three-dimensional structure of the genome is necessary to understand how gene expression is regulated. Recent experimental techniques such as Hi-C or ChIA-PET measure long-range chromatin interactions genome-wide but are experimentally elaborate, have limited resolution...

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Detalles Bibliográficos
Autores principales: Ibn-Salem, Jonas, Andrade-Navarro, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814980/
https://www.ncbi.nlm.nih.gov/pubmed/31653198
http://dx.doi.org/10.1186/s12864-019-6088-0