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The impact of D-cycloserine and sarcosine on in vivo frontal neural activity in a schizophrenia-like model

BACKGROUND: N-methyl-D-aspartate receptor (NMDAR) hypofunction has been proposed to underlie the pathogenesis of schizophrenia. Specifically, reduced function of NMDARs leads to altered balance between excitation and inhibition which further drives neural network malfunctions. Clinical studies sugge...

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Detalles Bibliográficos
Autores principales: Yao, Lulu, Wang, Zongliang, Deng, Di, Yan, Rongzhen, Ju, Jun, Zhou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814999/
https://www.ncbi.nlm.nih.gov/pubmed/31653237
http://dx.doi.org/10.1186/s12888-019-2306-1