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The impact of D-cycloserine and sarcosine on in vivo frontal neural activity in a schizophrenia-like model
BACKGROUND: N-methyl-D-aspartate receptor (NMDAR) hypofunction has been proposed to underlie the pathogenesis of schizophrenia. Specifically, reduced function of NMDARs leads to altered balance between excitation and inhibition which further drives neural network malfunctions. Clinical studies sugge...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814999/ https://www.ncbi.nlm.nih.gov/pubmed/31653237 http://dx.doi.org/10.1186/s12888-019-2306-1 |