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Fitness effects but no temperature-mediated balancing selection at the polymorphic Adh gene of Drosophila melanogaster
Polymorphism in the alcohol dehydrogenase (ADH) protein of Drosophila melanogaster, like genetic variation in many other enzymes, has long been hypothesized to be maintained by a selective trade-off between thermostability and enzyme activity. Two major Adh variants, named Fast and Slow, are distrib...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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National Academy of Sciences
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815130/ https://www.ncbi.nlm.nih.gov/pubmed/31594844 http://dx.doi.org/10.1073/pnas.1909216116 |