Fast-diffusing p75(NTR) monomers support apoptosis and growth cone collapse by neurotrophin ligands

The p75 neurotrophin (NT) receptor (p75(NTR)) plays a crucial role in balancing survival-versus-death decisions in the nervous system. Yet, despite 2 decades of structural and biochemical studies, a comprehensive, accepted model for p75(NTR) activation by NT ligands is still missing. Here, we presen...

Descripción completa

Detalles Bibliográficos
Autores principales: Marchetti, Laura, Bonsignore, Fulvio, Gobbo, Francesco, Amodeo, Rosy, Calvello, Mariantonietta, Jacob, Ajesh, Signore, Giovanni, Schirripa Spagnolo, Chiara, Porciani, David, Mainardi, Marco, Beltram, Fabio, Luin, Stefano, Cattaneo, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815156/
https://www.ncbi.nlm.nih.gov/pubmed/31515449
http://dx.doi.org/10.1073/pnas.1902790116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815156/
https://www.ncbi.nlm.nih.gov/pubmed/31515449
http://dx.doi.org/10.1073/pnas.1902790116

Ejemplares similares