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An ensemble of flexible conformations underlies mechanotransduction by the cadherin–catenin adhesion complex

The cadherin–catenin adhesion complex is the central component of the cell–cell adhesion adherens junctions that transmit mechanical stress from cell to cell. We have determined the nanoscale structure of the adherens junction complex formed by the α-catenin•β-catenin•epithelial cadherin cytoplasmic...

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Detalles Bibliográficos
Autores principales: Bush, Martin, Alhanshali, Bashir M., Qian, Shuo, Stanley, Christopher B., Heller, William T., Matsui, Tsutomu, Weiss, Thomas M., Nicholl, Iain D., Walz, Thomas, Callaway, David J. E., Bu, Zimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815173/
https://www.ncbi.nlm.nih.gov/pubmed/31591245
http://dx.doi.org/10.1073/pnas.1911489116