Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5

Activation of postsynaptic metabotropic glutamate receptors (mGluRs) modulates neuronal excitability and synaptic plasticity, while deregulation of mGluR signaling has been implicated in neurodevelopmental disorders. Overstimulation of mGluRs is restricted by the rapid endocytosis of receptors after...

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Detalles Bibliográficos
Autores principales: Scheefhals, Nicky, Catsburg, Lisa A.E., Westerveld, Margriet L., Blanpied, Thomas A., Hoogenraad, Casper C., MacGillavry, Harold D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815225/
https://www.ncbi.nlm.nih.gov/pubmed/31597090
http://dx.doi.org/10.1016/j.celrep.2019.08.102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815225/
https://www.ncbi.nlm.nih.gov/pubmed/31597090
http://dx.doi.org/10.1016/j.celrep.2019.08.102

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