Proteasomal Inhibition Redirects the PrP-Like Shadoo Protein to the Nucleus

The Shadoo protein (Sho) exhibits homology to the hydrophobic region of the cellular isoform of prion protein (PrP(C)). As prion-infected brains gradually accumulate infectivity-associated isoforms of prion protein (PrP(Sc)), levels of mature endogenous Sho become reduced. To study the regulatory ef...

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Detalles Bibliográficos
Autores principales: Kang, Sang-Gyun, Mays, Charles E., Daude, Nathalie, Yang, Jing, Kar, Satyabrata, Westaway, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815274/
https://www.ncbi.nlm.nih.gov/pubmed/31129810
http://dx.doi.org/10.1007/s12035-019-1623-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815274/
https://www.ncbi.nlm.nih.gov/pubmed/31129810
http://dx.doi.org/10.1007/s12035-019-1623-1

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