Cargando…

Dynamic metabolic modelling of overproduced protein secretion in Streptomyces lividans using adaptive DFBA

BACKGROUND: Streptomyces lividans is an appealing host for the production of proteins of biotechnological interest due to its relaxed exogenous DNA restriction system and its ability to secrete proteins directly to the medium through the major Sec or the minor Tat routes. Often, protein secretion di...

Descripción completa

Detalles Bibliográficos
Autores principales: Valverde, Jósé R., Gullón, Sonia, García-Herrero, Clara A., Campoy, Iván, Mellado, Rafael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815373/
https://www.ncbi.nlm.nih.gov/pubmed/31655540
http://dx.doi.org/10.1186/s12866-019-1591-7