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Dynamic metabolic modelling of overproduced protein secretion in Streptomyces lividans using adaptive DFBA
BACKGROUND: Streptomyces lividans is an appealing host for the production of proteins of biotechnological interest due to its relaxed exogenous DNA restriction system and its ability to secrete proteins directly to the medium through the major Sec or the minor Tat routes. Often, protein secretion di...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815373/ https://www.ncbi.nlm.nih.gov/pubmed/31655540 http://dx.doi.org/10.1186/s12866-019-1591-7 |