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A comparison of the statistical performance of different meta-analysis models for the synthesis of subgroup effects from randomized clinical trials

BACKGROUND: When investigating subgroup effects in meta-analysis, it is unclear whether accounting in meta-regression for between-trial variation in treatment effects, but not between-trial variation in treatment interaction effects when such effects are present, leads to biased estimates, coverage...

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Detalles Bibliográficos
Autores principales: da Costa, Bruno R., Sutton, Alex J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815379/
https://www.ncbi.nlm.nih.gov/pubmed/31655550
http://dx.doi.org/10.1186/s12874-019-0831-8