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Dynein activating adaptor BICD2 controls radial migration of upper-layer cortical neurons in vivo

For the proper organization of the six-layered mammalian neocortex it is required that neurons migrate radially from their place of birth towards their designated destination. The molecular machinery underlying this neuronal migration is still poorly understood. The dynein-adaptor protein BICD2 is a...

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Detalles Bibliográficos
Autores principales: Will, Lena, Portegies, Sybren, van Schelt, Jasper, van Luyk, Merel, Jaarsma, Dick, Hoogenraad, Casper C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815425/
https://www.ncbi.nlm.nih.gov/pubmed/31655624
http://dx.doi.org/10.1186/s40478-019-0827-y