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Early treatment with ambrisentan of mildly elevated mean pulmonary arterial pressure associated with systemic sclerosis: a randomized, controlled, double-blind, parallel group study (EDITA study)

OBJECTIVE: The objective of this randomized, placebo-controlled, double-blind, parallel group, trial was to assess the effect of ambrisentan on mean pulmonary arterial pressure (mPAP) in patients with systemic sclerosis (SSc) and mildly elevated pulmonary hypertension (PH). METHODS: Thirty-eight SSc...

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Detalles Bibliográficos
Autores principales: Pan, Zixuan, Marra, Alberto M., Benjamin, Nicola, Eichstaedt, Christina A., Blank, Norbert, Bossone, Eduardo, Cittadini, Antonio, Coghlan, Gerry, Denton, Christopher P., Distler, Oliver, Egenlauf, Benjamin, Fischer, Christine, Harutyunova, Satenik, Xanthouli, Panagiota, Lorenz, Hanns-Martin, Grünig, Ekkehard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815440/
https://www.ncbi.nlm.nih.gov/pubmed/31655622
http://dx.doi.org/10.1186/s13075-019-1981-0