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Transcription Factor p53 Suppresses Tumor Growth by Prompting Pyroptosis in Non-Small-Cell Lung Cancer

OBJECTIVE: To evaluate the effect of p53 on pyroptosis and its inhibitory role on tumor growth in non-small-cell lung cancer (NSCLC). METHODS: The correlation of p53 and pyroptosis was determined in tumor tissues of NSCLC patients. The pyroptotic level was detected in A549 cells to clarify the effec...

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Detalles Bibliográficos
Autores principales: Zhang, Tianze, Li, Yongchao, Zhu, Ruidong, Song, Pengcheng, Wei, Youlei, Liang, Tian, Xu, Guangquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815571/
https://www.ncbi.nlm.nih.gov/pubmed/31737176
http://dx.doi.org/10.1155/2019/8746895