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Transcription Factor p53 Suppresses Tumor Growth by Prompting Pyroptosis in Non-Small-Cell Lung Cancer
OBJECTIVE: To evaluate the effect of p53 on pyroptosis and its inhibitory role on tumor growth in non-small-cell lung cancer (NSCLC). METHODS: The correlation of p53 and pyroptosis was determined in tumor tissues of NSCLC patients. The pyroptotic level was detected in A549 cells to clarify the effec...
Autores principales: | Zhang, Tianze, Li, Yongchao, Zhu, Ruidong, Song, Pengcheng, Wei, Youlei, Liang, Tian, Xu, Guangquan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815571/ https://www.ncbi.nlm.nih.gov/pubmed/31737176 http://dx.doi.org/10.1155/2019/8746895 |
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