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Fusobacterium nucleatum Facilitates Apoptosis, ROS Generation, and Inflammatory Cytokine Production by Activating AKT/MAPK and NF-κB Signaling Pathways in Human Gingival Fibroblasts

Fusobacterium nucleatum (F. nucleatum) plays key roles in the initiation and progression of periodontitis. However, the pathogenic effect of F. nucleatum on human oral tissues and cells has not been fully evaluated. In this study, we aimed to analyze the pathogenic effects of F. nucleatum on human g...

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Detalles Bibliográficos
Autores principales: Kang, Wenyan, Jia, Zhilong, Tang, Di, Zhang, Zhanwei, Gao, Hui, He, Kunlun, Feng, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815639/
https://www.ncbi.nlm.nih.gov/pubmed/31737164
http://dx.doi.org/10.1155/2019/1681972