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Dissecting the role of the germinal vesicle nuclear envelope and soluble content in the process of somatic cell remodelling and reprogramming

Differentiated nuclei can be reprogrammed/remodelled to totipotency after their transfer to enucleated metaphase II (MII) oocytes. The process of reprogramming/remodelling is, however, only partially characterized. It has been shown that the oocyte nucleus (germinal vesicle – GV) components are esse...

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Detalles Bibliográficos
Autores principales: FULKA, Helena, OGURA, Atsuo, LOI, Pasqualino, FULKA, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815741/
https://www.ncbi.nlm.nih.gov/pubmed/31423000
http://dx.doi.org/10.1262/jrd.2019-017