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PTC-209 Anti-Cancer Effects Involved the Inhibition of STAT3 Phosphorylation

Introduction: Lung, breast, and colorectal cancers are the leading causes of cancer-related deaths despite many therapeutic options, including targeted therapy and immunotherapies. Methods: Here, we investigated the impact of PTC-209, a small-molecule Bmi-1 inhibitor, on human cancer cell viability...

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Detalles Bibliográficos
Autores principales: Sulaiman, Shahrazad, Arafat, Kholoud, Iratni, Rabah, Attoub, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815748/
https://www.ncbi.nlm.nih.gov/pubmed/31695609
http://dx.doi.org/10.3389/fphar.2019.01199