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A Novel Octapeptide Derived From G Protein-Coupled Receptor 124 Improves Cognitive Function Via Pro-Angiogenesis In A Rat Model Of Chronic Cerebral Hypoperfusion-Induced Vascular Dementia

PURPOSE: The lack of effective therapies mandates the development of new treatment strategies for vascular dementia (VaD). G protein-coupled receptor 124 (GPR124) may be a therapeutic target for angiogenesis-related diseases of CNS, including VaD. The GCPF peptide is a truncated and screened fragmen...

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Detalles Bibliográficos
Autores principales: Xiao, Ying, Shen, Hong, Li, Rui, Zhou, Xia, Xiao, Hong, Yan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815762/
https://www.ncbi.nlm.nih.gov/pubmed/31695334
http://dx.doi.org/10.2147/DDDT.S226473