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Mitofusin2, a rising star in acute‐on‐chronic liver failure, triggers macroautophagy via the mTOR signalling pathway

Acute‐on‐chronic liver failure (ACLF) is a life‐threatening syndrome with poor prognosis. Several studies have begun to prove that mitochondria play a crucial role in liver failure. Mitofusin2 (Mfn2) plays a key role in maintaining the integrity of mitochondrial morphology and function. However, the...

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Detalles Bibliográficos
Autores principales: Xue, Ran, Zhu, Xuemin, Jia, Lin, Wu, Jing, Yang, Jing, Zhu, Yueke, Meng, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815802/
https://www.ncbi.nlm.nih.gov/pubmed/31557386
http://dx.doi.org/10.1111/jcmm.14658