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Elevated hsa‐miR‐590‐3p expression down‐regulates HMGB2 expression and contributes to the severity of IgA nephropathy

Peripheral blood mononuclear cells (PBMCs) play important roles in the pathogenesis of IgA nephropathy (IgAN). Our study aimed to provide a deep understanding of IgAN and focused on the dysregulation of hsa‐miR‐590‐3p and its target gene HMGB2 in PBMCs. Three gene expression profile datasets (GSE147...

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Detalles Bibliográficos
Autores principales: Zhai, Yaling, Qi, Yuanyuan, Long, Xiaoqing, Dou, Yanna, Liu, Dong, Cheng, Genyang, Xiao, Jing, Liu, Zhangsuo, Zhao, Zhanzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815813/
https://www.ncbi.nlm.nih.gov/pubmed/31557418
http://dx.doi.org/10.1111/jcmm.14582