Cargando…

EGR1 interacts with DNMT3L to inhibit the transcription of miR‐195 and plays an anti‐apoptotic role in the development of gastric cancer

EGR1 regulates the expression of its downstream target genes and may exert different biological effects in different tumours. We found that the expression of EGR1 was increased in gastric cancer (GC), and silencing the expression of EGR1 promoted the apoptosis of GC cells. Moreover, overexpression o...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Yang, Wu, Fei, Zhang, Jing, Sun, Ruifang, Li, Fang, Li, Yulong, Chang, Su’e, Wang, Lumin, Wang, Xiaofei, Liu, Liying, Huang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815817/
https://www.ncbi.nlm.nih.gov/pubmed/31515938
http://dx.doi.org/10.1111/jcmm.14597