Cargando…

Preclinical evaluation of exemestane as a novel chemotherapy for gastric cancer

CYP19A1/aromatase (Ar) is a prognostic biomarker of gastric cancer (GCa). Ar is a critical enzyme for converting androstenedione to oestradiol in the steroidogenesis cascade. For decades, Ar has been targeted with Ar inhibitors (ARIs) in gynaecologic malignancies; however, it is unexplored in GCa. A...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Juan‐Cheng, Chang, Ning, Wu, Deng‐Chyang, Cheng, Wei‐Chung, Chung, Wei‐Min, Chang, Wei‐Chun, Lei, Fu‐Ju, Liu, Chung‐Jung, Wu, I‐Chen, Lai, Hsueh‐Chou, Ma, Wen‐Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815818/
https://www.ncbi.nlm.nih.gov/pubmed/31557413
http://dx.doi.org/10.1111/jcmm.14605