Cargando…
Preclinical evaluation of exemestane as a novel chemotherapy for gastric cancer
CYP19A1/aromatase (Ar) is a prognostic biomarker of gastric cancer (GCa). Ar is a critical enzyme for converting androstenedione to oestradiol in the steroidogenesis cascade. For decades, Ar has been targeted with Ar inhibitors (ARIs) in gynaecologic malignancies; however, it is unexplored in GCa. A...
Autores principales: | Yang, Juan‐Cheng, Chang, Ning, Wu, Deng‐Chyang, Cheng, Wei‐Chung, Chung, Wei‐Min, Chang, Wei‐Chun, Lei, Fu‐Ju, Liu, Chung‐Jung, Wu, I‐Chen, Lai, Hsueh‐Chou, Ma, Wen‐Lung |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815818/ https://www.ncbi.nlm.nih.gov/pubmed/31557413 http://dx.doi.org/10.1111/jcmm.14605 |
Ejemplares similares
-
Cholesterol import and steroidogenesis are biosignatures for gastric cancer patient survival
por: Chang, Wei-Chun, et al.
Publicado: (2016) -
Ursolic acid silences CYP19A1/aromatase to suppress gastric cancer growth
por: Ma, Wen‐Lung, et al.
Publicado: (2022) -
The role of bile acids in cellular invasiveness of gastric cancer
por: Wu, Yu-Chung, et al.
Publicado: (2018) -
Stromal C-type lectin receptor COLEC12 integrates H. pylori, PGE2-EP2/4 axis and innate immunity in gastric diseases
por: Chang, Lin-Li, et al.
Publicado: (2018) -
Betulinic Acid Inhibits the Stemness of Gastric Cancer Cells by Regulating the GRP78-TGF-β1 Signaling Pathway and Macrophage Polarization
por: Chen, Jen-Lung, et al.
Publicado: (2023)